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Thalidomide for Type 1 Cryoglobulinemic Vasculopathy
Alia Sampson, MD;
Jeffrey P. Callen, MD
Division of Dermatology, Department of Medicine, University of Louisville School of Medicine, Louisville, Ky
Arch Dermatol. 2006;142:972-974.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 46-year-old African American woman was referred to 1 of us (J.P.C.) for evaluation and treatment of a vasculopathy in November 2003. She had been well until October 2003, when, following an upper respiratory tract infection, she developed painful lesions on her calves. She had been treated with a short course of oral prednisone by the referring dermatologist, which resulted in minimal improvement. Review of the pathologic specimen, which was obtained by the referring dermatologist, confirmed a noninflammatory vasculopathy in which there was plugging of multiple small cutaneous vessels with a proteinaceous material. Laboratory evaluation revealed a monoclonal spike on protein electrophoresis and a positive qualitative cryofibrinogen finding. Findings from complete blood cell count and comprehensive chemical analysis were normal, and findings for anticardiolipin antibody, antineutrophilic cytoplasmic antibody, and hepatitis C antibody were negative.
Physical examination on referral revealed an obese African American . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
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