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  Vol. 142 No. 8, August 2006 TABLE OF CONTENTS
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  The Cutting Edge: Challenges in Medical and Surgical Therapeutics
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Thalidomide for Type 1 Cryoglobulinemic Vasculopathy

Alia Sampson, MD; Jeffrey P. Callen, MD
Division of Dermatology, Department of Medicine, University of Louisville School of Medicine, Louisville, Ky

Arch Dermatol. 2006;142:972-974.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 46-year-old African American woman was referred to 1 of us (J.P.C.) for evaluation and treatment of a vasculopathy in November 2003. She had been well until October 2003, when, following an upper respiratory tract infection, she developed painful lesions on her calves. She had been treated with a short course of oral prednisone by the referring dermatologist, which resulted in minimal improvement. Review of the pathologic specimen, which was obtained by the referring dermatologist, confirmed a noninflammatory vasculopathy in which there was plugging of multiple small cutaneous vessels with a proteinaceous material. Laboratory evaluation revealed a monoclonal spike on protein electrophoresis and a positive qualitative cryofibrinogen finding. Findings from complete blood cell count and comprehensive chemical analysis were normal, and findings for anticardiolipin antibody, antineutrophilic cytoplasmic antibody, and hepatitis C antibody were negative.

Physical examination on referral revealed an obese African American . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT

AUTHOR INFORMATION







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