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Two "Positive" Studies of Probiotics for Atopic Dermatitis
Or Are They?
Hywel C. Williams, PhD
Arch Dermatol. 2006;142:1201-1203.
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Commentary 1 on: Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind, placebo-controlled trial Viljanen M, Savilahti E, Haahtela T, et al Allergy. 2005;60:494-500
Question: In infants with established atopic dermatitis (AD) and suspected cow's milk allergy, does administration of probiotics (Lactobacillus GG or a mixture of 4 probiotic strains) improve Scoring Atopic Dermatitis (SCORAD) index severity scores when compared with placebo at 4 weeks?
Design: Randomized, controlled, double-blind, placebo-controlled study.
Setting: Hospital skin and allergy center serving local health centers in Helsinki, Finland.
Participants: Two hundred thirty infants, aged 1.4 to 11.9 months, with AD diagnosed by a physician and with symptoms suggestive of cow's milk allergy.
Intervention: Three groups were tested: the first (n = 80) was given Lactobacillus rhamnosus GG at a dose of 5 x 109 colony-forming units; the second (n = 76), a mixture of 4 probiotics strains; and the third, . . . [Full Text of this Article] Comment
AUTHOR INFORMATION
Centre of Evidence-Based Dermatology, Queen's Medical Centre University Hospital, National Health Service Trust, Nottingham, England
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Prebiotics Reduce the Incidence of Atopic Dermatitis in High-Risk Infants
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