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Arch Dermatol. 2006;142:1221-1226.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Tuberculosis verrucosa cutis.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histologic sections showed a central ulceration surrounded by a dense infiltration of histiocytes and lymphocytes. There was an area of caseating necrosis. A Fite stain demonstrated numerous acid-fast bacilli, and a periodic acid–Schiff stain was negative for fungal microorganisms. Another biopsy specimen (not shown) demonstrated pseudocarcinomatous hyperplasia with a suppurative granulomatous infiltrate with multinucleated histiocytes, but the results of a Fite stain were negative. The skin biopsy specimen that was sent for culture yielded Mycobacteria tuberculosis. The organism showed sensitivity to ethambutol hydrochloride, isoniazid, and rifampin but was resistance to streptomycin.

The local health department started the patient on a regimen of isoniazid, rifampin, ethambutol, and pyrazinamide, which resulted in rapid improvement of the cutaneous lesion within a few weeks. Additional history revealed that her husband had previously been treated for pulmonary tuberculosis.

DISCUSSION

Tuberculosis verrucosa cutis is a form of cutaneous tuberculosis that results from exogenous inoculation into the . . . [Full Text of this Article]

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Arch Dermatol. 2006;142(9):1221-1226.
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