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Dermal Plaques of the Face and Scalp—Diagnosis
Arch Dermatol. 2007;143(1):109-114.
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Diagnosis: Platelike osteoma cutis.
MICROSCOPIC AND LABORATORY FINDINGS
Histologic evaluation showed lamellar bone with a fatty marrow that extended from the midreticular dermis into the subcutaneous fat. Haversian canals and numerous osteoblasts were present. Polarization showed birefringence consistent with lamellar ossification. A general physical examination of the patient revealed no abnormalities. The results of laboratory investigations, including circulating levels of calcium, phosphorus, and parathyroid hormone; a complete blood cell count; urinalysis; and serum chemistry studies, were normal.
DISCUSSION
Osteoma cutis is an uncommon occurrence. Cutaneous ossification is classified as either primary or secondary.1 Secondary cutaneous bone formation represents about 85% of dermal mineralization; however, mature bone formation is not observed.2-3 Primary osteoma cutis, which represents true bone amartothic formation and typically demonstrates mature lamellar and/or osteonic bone, is infrequently encountered; only 10 primary osteomas were identified in a review of 20 000 consecutive skin biopsy specimens.2, 4-5 Circulating levels of calcium and phosphorus are normal, and the cutaneous bone arises idiopathically . . . [Full Text of this Article]
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Arch Dermatol. 2007;143(1):109-114.
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