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Reflectance-Mode Confocal Microscopy for the Diagnosis of Sebaceous Hyperplasia In vivo
Iva Propperova, MD;
Richard G. B. Langley, MD
Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia
Arch Dermatol. 2007;143(1):134.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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A 54-year-old man was seen with an enlarging papule with central depression and telangiectasias on his left cheek. A clinical diagnosis of basal cell carcinoma was made with a differential diagnosis of sebaceous hyperplasia.
We investigated the use of confocal scanning laser microscopy (CSLM) to help discriminate between these diagnoses. Imaging revealed an enlarged sebaceous lobule consisting of cuboidal cells with centrally located nuclei and a dilated sebaceous duct (Figure 1). A diagnosis of sebaceous hyperplasia was made in vivo by CSLM. Excellent confocal-histopathologic correlation was obtained confirming sebaceous hyperplasia.
Figure appears in full text version.
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Two other patients with similar lesions were examined with CSLM: a 52-year-old woman with a lesion on the glabella that had an enlarged sebaceous lobule (Figure 2) and a 48-year-old man with a lesion on his left cheek that had a dilated sebaceous duct with a . . . [Full Text of this Article]
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