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Progressive Extragenital Lichen Sclerosus Successfully Treated With Narrowband UV-B Phototherapy
Rand L. Colbert, MD;
Melissa P. Chiang, MD;
Christopher S. Carlin, MD;
Matthew Fleming, MD
Arch Dermatol. 2007;143(1):19-20.
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REPORT OF A CASE
A 76-year-old woman with hypertension and hepatitis C presented with a 10-year history of sclerotic, atrophic, ivory-white plaques with violaceous borders on the upper part of her trunk and on her arms, waistline, and anogenital areas (Figure 1). The plaques were gradually extending and becoming more pruritic. A biopsy revealed findings diagnostic of lichen sclerosus (LS), including an atrophic epidermis, homogenized upper dermis, and sparse chronic inflammation in the middle dermis, below the homogenized collagen.
Figure appears in full text version.
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Figure 1. Before narrowband UV-B therapy. White, slightly indurated, atrophic plaque with thin scale and erythema at the periphery.
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The patient experienced a modest response to topical tacrolimus therapy, followed by more substantial improvement with topical clobetasol propionate therapy. However, several months later, she returned with worsening pruritus and enlargement of the plaques on her neck, waist, and . . . [Full Text of this Article]
CLINICAL CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
Medical College of Wisconsin, Milwaukee
RELATED LETTER
Narrowband UV-B Phototherapy for Extragenital Lichen Sclerosus
Alexander Kreuter and Thilo Gambichler
Arch Dermatol. 2007;143(9):1213.
EXTRACT
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Narrowband UV-B Phototherapy for Extragenital Lichen Sclerosus
Kreuter and Gambichler
Arch Dermatol 2007;143:1213-1213.
FULL TEXT
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