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Rand L. Colbert, MD; Melissa P. Chiang, MD; Christopher S. Carlin, MD; Matthew Fleming, MD

Arch Dermatol. 2007;143(1):19-20.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 76-year-old woman with hypertension and hepatitis C presented with a 10-year history of sclerotic, atrophic, ivory-white plaques with violaceous borders on the upper part of her trunk and on her arms, waistline, and anogenital areas (Figure 1). The plaques were gradually extending and becoming more pruritic. A biopsy revealed findings diagnostic of lichen sclerosus (LS), including an atrophic epidermis, homogenized upper dermis, and sparse chronic inflammation in the middle dermis, below the homogenized collagen.

Figure appears in full text version. Figure 1. Before narrowband UV-B therapy. White, slightly indurated, atrophic plaque with thin scale and erythema at the periphery.

The patient experienced a modest response to topical tacrolimus therapy, followed by more substantial improvement with topical clobetasol propionate therapy. However, several months later, she returned with worsening pruritus and enlargement of the plaques on her neck, waist, and . . . [Full Text of this Article]

CLINICAL CHALLENGE

SOLUTION

COMMENT

AUTHOR INFORMATION

Medical College of Wisconsin, Milwaukee

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