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Nodular Lesions on the Arm—Diagnosis
Arch Dermatol. 2007;143(10):1323-1328.
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Diagnosis: Lobomycosis.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
The lesional biopsy specimen revealed numerous and diffuse inflammatory granulomas in the dermis. The granulomas were composed of histiocytes and giant cells containing numerous phagocytosed thick-walled cells. An asteroid body was also seen. The GMS stain showed the typical yeasts of lobomycosis in chains of uniform round to oval cells.
The nodules were completely excised, and the patient was given itraconazole, 200 mg/d, for 6 months as an attempt to prevent disease relapse.
DISCUSSION
Lobomycosis, also known as Lobo disease, is a chronic fungal disease that affects the skin and subcutaneous tissue.1 It was first described in Brazil in 1931 by Jorge Lobo.2 The etiologic agent has been named, after much controversy, as Lacazia loboi.3
The disease affects people living in the tropical zone of the New World.2 It has been described mostly in Brazil,4 but it has also been found in Colombia, Surinam, Costa Rica, Venezuela, French Guiana, and . . . [Full Text of this Article]
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Anette Chrusciak-Talhari, Carolina Talhari, Mônica Nunes de Souza Santos, Luis Carlos Ferreira, and Sinésio Talhari
Arch Dermatol. 2007;143(10):1323-1328.
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