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Arch Dermatol. 2007;143(10):1323-1328.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cutaneous Blastomyces dermatitidis infection.

MICROSCOPIC AND LABORATORY FINDINGS AND CLINICAL COURSE

At the initial visit, findings from the potassium hydroxide touch-preparation smear from the right popliteal fossa plaque revealed large 5- to 15-µm-diameter refractile ovoid to circular yeast forms with occasional broad-based budding. Histologic examination results from the shave biopsy specimen revealed marked pseudoepitheliomatous hyperplasia, scattered intraepidermal and intradermal neutrophilic microabscesses, marked epidermal spongiosis, and an underlying suppurative chronic inflammatory infiltrate with multinucleated giant and plasma cells. Scattered broad-based budding yeast forms were seen within the inflammatory infiltrate. The periodic acid–Schiff stain was positive for the presence of fungus.

The patient was diagnosed as having systemic blastomycosis, with osteomyelitis of the navicular bone due to blastomycosis infection, pulmonary scarring in the right upper lobe consistent with chronic pulmonary blastomycosis, and cutaneous blastomycosis. Treatment with oral itraconazole, 200 mg twice a day, was initiated.

DISCUSSION

First described by Gilchrist¹ in 1894, B dermatitidis is a thermal dimorphic fungus endemic to the central United . . . [Full Text of this Article]

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Arch Dermatol. 2007;143(10):1323-1328.
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