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Zakiya M. Pressley, MD; Jovonne K. Foster, MS; Paul Kolm, PhD; Liping Zhao, MS; Felicia Warren, BA; William Weintraub, MD; Bauer E. Sumpio, MD, PhD; Suephy C. Chen, MD, MS

Arch Dermatol. 2007;143(10):1331-1333.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Quantitative evaluation of cutaneous lesions in clinical trials can be problematic for diseases such as lower extremity ulcers, vitiligo, and alopecia. Because of the irregular shapes of these lesions, calculation of their circumference, diameter, and area can be cumbersome using traditional manual tracings. As a result, most trials using manual tracings will measure the longest diameter or approximate circumference of a target lesion. To compound the problem, in some diseases, access to the lesions is difficult. These lesions include erosions of the oral or genital mucosa. New software is now readily available that incorporates digital technologies and allows for digital image analysis (DIA) to circumvent these traditional problems. Digital image analysis provides a means to calculate desired target diameter and . . . [Full Text of this Article]

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