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COMMENTS AND OPINIONS
Sodium Thiosulfate as First-Line Treatment for Calciphylaxis
Felix Ackermann, MD;
Annabelle Levy, MD;
Eric Daugas, MD, PhD;
Noel Schartz, MD, PhD;
Anne Riaux, MD;
Christian Derancourt, MD;
Pablo Urena, MD;
Celeste Lebbé, MD, PhD
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The case report by Robinson et al1 concerning a woman with a renal transplant whose calciphylaxis was successfully treated with cinacalcet hydrochloride is interesting but must be interpreted with caution. We present herein our experience with a 45-year-old woman who underwent renal transplantation 10 years ago for treatment of nephropathy of undetermined origin.
Report of a Case
The patient's renal function deteriorated because of chronic allograft nephropathy and uncontrolled diabetes. On her left leg, she developed ulcerations surrounded by livedoid borders that rapidly became painful and resistant to local wound care. Despite treatment with analgesics and antibiotics, her condition worsened, and she developed septic shock requiring amputation of her left leg. A week later, ulcerations appeared on the right leg. Serum phosphate and calcium levels were high. . . . [Full Text of this Article]
Comment
AUTHOR INFORMATION
RELATED LETTERS
Calciphylaxis Responding to Sodium Thiosulfate Therapy
Brian L. Baker, Carrie A. Fitzgibbons, and Lucinda S. Buescher
Arch Dermatol. 2007;143(2):269-270.
EXTRACT
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Sodium Thiosulfate as First-Line Treatment for Calciphylaxis—Reply
Maria R. Robinson, Joshua J. Augustine, and Neil J. Korman
Arch Dermatol. 2007;143(10):1338.
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RELATED ARTICLE
Cinacalcet for the Treatment of Calciphylaxis
Maria R. Robinson, Joshua J. Augustine, and Neil J. Korman
Arch Dermatol. 2007;143(2):152-154.
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