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VIGNETTES
Delayed Wound Healing Following Treatment With Low-Dose Interferon Alfa-2b for Cutaneous Melanoma
Alfred F. Ammoury, MD;
Fouad El Sayed, MD;
Jacques Bazex, MD
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Adjuvant therapies for cutaneous melanoma have been well studied, and to our knowledge only high-dose interferon alfa-2b shows reproducible benefit.1 Efforts to improve the toxic effects profile of high-dose regimens have included the use of lower doses. We report a case of delayed wound healing secondary to treatment with low-dose interferon alfa-2b for cutaneous melanoma.
Report of a Case
A 23-year-old woman, skin phototype II, presented with a 3-month history of a slowly growing, nodular, achromic lesion on the left calf. Apart from frequent sunburn, she had been well. Histologic examination revealed an ulcerated superficial spreading melanoma 4.8-mm thick, Clark level 4, without signs of regression. Her treatment consisted of a 3-cm-wide excision followed by LLL-plasty. Sentinel lymph node dissection of the left inguinal region revealed 3 nonmetastatic lymph nodes. The disease was classified as a stage IIC (2002 American Joint Committee on . . . [Full Text of this Article] Comment
AUTHOR INFORMATION
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