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  Vol. 143 No. 10, October 2007 TABLE OF CONTENTS
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 •Viral Infections
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VIGNETTES
Intractable Wounds From a Herpes Simplex Infection in an Immunosuppressed Patient With Rheumatoid Arthritis

Takaaki Hanafusa, MD; Yuji Yamaguchi, MD, PhD; Shun Kitaba, MD; Ichiro Katayama, MD, PhD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Herpes simplex virus (HSV) infections, characterized by painful grouped vesicles with erythema occurring on perioral and/or pubic areas, affect over 40 million people in the United States,1 where 1.6 million people are infected annually with HSV-2.2 The diagnosis of HSV is generally easy, but it becomes difficult in immunosuppressed populations.3

Report of a Case

Our patient was a 76-year-old Japanese woman without human immunodeficiency virus but with rheumatoid arthritis (RA). She had been treated with prednisolone (5 mg/d) and methotrexate (4 mg/wk) for more than 20 years and had also been treated for multiple recurrent ulcers on her lower legs caused by RA-related leukocytoclastic vasculitis. Multiple bullae on her legs were successfully treated with a prednisolone dose increase to 20 mg/d. However, multiple painful ulcers appeared on her buttocks and gradually increased in both number and size (Figure 1. . . [Full Text of this Article]


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RELATED ARTICLE

Chronic Herpes Simplex Infection in Cutaneous T-Cell Lymphomas
Eric C. Vonderheid, Harold J. Milstein, Kenneth D. Thompson, and Brian C. Wu
Arch Dermatol. 1980;116(9):1018-1022.
ABSTRACT  






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