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VIGNETTES
Intractable Wounds From a Herpes Simplex Infection in an Immunosuppressed Patient With Rheumatoid Arthritis
Takaaki Hanafusa, MD;
Yuji Yamaguchi, MD, PhD;
Shun Kitaba, MD;
Ichiro Katayama, MD, PhD
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Herpes simplex virus (HSV) infections, characterized by painful grouped vesicles with erythema occurring on perioral and/or pubic areas, affect over 40 million people in the United States,1 where 1.6 million people are infected annually with HSV-2.2 The diagnosis of HSV is generally easy, but it becomes difficult in immunosuppressed populations.3
Report of a Case
Our patient was a 76-year-old Japanese woman without human immunodeficiency virus but with rheumatoid arthritis (RA). She had been treated with prednisolone (5 mg/d) and methotrexate (4 mg/wk) for more than 20 years and had also been treated for multiple recurrent ulcers on her lower legs caused by RA-related leukocytoclastic vasculitis. Multiple bullae on her legs were successfully treated with a prednisolone dose increase to 20 mg/d. However, multiple painful ulcers appeared on her buttocks and gradually increased in both number and size (Figure 1. . . [Full Text of this Article] Comment
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ABSTRACT
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