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Massimo Carducci, MD; Roberta Calcaterra, MD; Massimo Rinaldi, MD; Anna Mussi, MD; Giuditta Viola, MD; Irene Venturo, MD; Letizia Perracchio, MD; Gennaro Franco, MD; Massimo Lopez, MD; Aldo Morrone, MD

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Report of a Case

A 61-year-old man had infiltrative squamous cell carcinoma of the penis and widespread metastasis to the lymph nodes diagnosed 2 months before he was seen in our department (Figure 1). He had been treated with fluorouracil and cisplatin.

Figure appears in full text version. Figure 1. Keratinizing squamous cell carcinoma involving the perinodal tissue (hematoxylin-eosin, original magnification x20).

When he came to our attention, he also had a 3-month history of Raynaud phenomenon. In the last month, this condition had become associated with necrotic lesions on the fingertips of the second and third fingers of the right hand (Figure 2A). Similar but smaller lesions were also present on the fingertip of the second finger of the left hand and on the . . . [Full Text of this Article]

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