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Three-Dimensional Images and Vessel Rendering Using Optical Coherence Tomography
Meghan W. Thomas, BS, MBA;
James M. Grichnik, MD, PhD;
Joseph A. Izatt, PhD
University of North Carolina School of Medicine (Ms Thomas) and Duke University Medical Center (Drs Grichnik and Izatt), Durham
Arch Dermatol. 2007;143(11):1468-1469.
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Optical coherence tomography (OCT) is an emerging technology in dermatology. Translating the principles of ultrasound to use with light waves, OCT captures in vivo images allowing for 3-dimensional reconstruction and Doppler flow measurements. Compared with confocal microscopy, standard OCT has a greater depth of penetration but lower resolution. This places the technology between traditional ultrasound and confocal microscopy in the trade-off between depth penetration and surface resolution (Figure 1). Optical coherence tomography creates an image by splitting an infrared laser into a reference arm and a sample arm (Figure 2). The sample arm scans a designated region of skin, and an interferometer then compares the signal from the skin with a reference arm. Mathematical processing of the differences results in image creation. The depth of penetration and resolution of OCT is determined . . . [Full Text of this Article]
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