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Generalized Papules in a Patient With Acute Myeloid Leukemia—Quiz Case
Kyoko Nakahigashi, MD;
Miki Tanioka, MD, PhD;
Yoshiki Miyachi, MD, PhD
Kyoto University, Kyoto, Japan
Arch Dermatol. 2007;143(12):1583-1588.
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REPORT OF A CASE
A 58-year-old Japanese man, who had been followed up and received blood transfusions regularly for myelodysplastic syndrome (refractory anemia with an excess of blast cells) for 1 year, developed acute myeloid leukemia. He had pancytopenia, with a white blood cell (WBC) count of 800 cells/µL (to convert to x 109/L, multiply by 0.001), neutropenia (7.0 % of WBCs), and increased circulating blast cell count (58% of WBCs). He had received fluconazole as antifungal prophylaxis.
He commenced chemotherapy via a central venous catheter. On day 11, he had a high fever, and a blood culture was taken. On day 13, he presented with asymptomatic papules on the upper limbs (Figure 1), which spread over the trunk, face, and lower limbs on the nextday. These papules were 5 to 10 mm in diameter and some appeared purpuric. He . . . [Full Text of this Article]
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Generalized Papules in a Patient With Acute Myeloid Leukemia—Diagnosis
Arch Dermatol. 2007;143(12):1583-1588.
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