This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on ISI (2)  • Contact me when this article is cited  Related Content  • Related letters  • Related article  • Similar articles in this journal  Topic Collections  • Psoriasis  • Drug Therapy  • Adverse Effects  • Alert me on articles by topic

Psoriasiform Eruptions During Anti–TNF- Treatment: Psoriasis or Not?

Julien Seneschal, MD; Sébastien Lepreux, MD; Brigitte Milpied, MD; Thierry Schaeverbeke, MD, PhD; Alain Taïeb, MD, PhD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with interest the report by de Gannes et al¹ concerning psoriasis triggered by tumor necrosis factor (TNF-) inhibitors. The paradoxical induction of psoriasislike eruption in patients treated with anti–TNF- agents was first described by Verea et al² in 2004. Since that time, more than 70 cases of psoriasiform eruptions have been reported in patients with autoinflammatory diseases who are undergoing treatment with anti–TNF- agents. The major clinical presentation is palmoplantar pustulosis sometimes accompanied by guttate or plaquelike psoriasis. In 20 cases, histologic findings were consistent with psoriasis. In other reports, skin biopsy findings were not typical of psoriasis or showed a lichenoid² pattern. However, psoriasiform eruptions were not always analyzed histologically.

Our research group³ has described 8 patients (3 women and 5 men; mean age, 45 years) who experienced psoriasiform . . . [Full Text of this Article]

AUTHOR INFORMATION

RELATED LETTERS

Psoriasiform Eruptions During Anti–TNF- Treatment: Psoriasis or Not?—Reply
Gillian C. de Gannes, Mehran Ghoreishi, Janet Pope, Anthony Russell, David Bell, Stewart Adams, Kamran Shojania, Magdalena Martinka, and Jan P. Dutz
Arch Dermatol. 2007;143(12):1595.
EXTRACT | FULL TEXT  

The Use of Patch Tests in Determining Hypersensitivity to Etanercept and Infliximab
Lidian L. A. Lecluse, Gamze Piskin, and Jan D. Bos
Arch Dermatol. 2008;144(8):1070-1071.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Psoriasis and Pustular Dermatitis Triggered by TNF- Inhibitors in Patients With Rheumatologic Conditions
Gillian C. de Gannes, Mehran Ghoreishi, Janet Pope, Anthony Russell, David Bell, Stewart Adams, Kamran Shojania, Magdalena Martinka, and Jan P. Dutz
Arch Dermatol. 2007;143(2):223-231.
ABSTRACT | FULL TEXT