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Psoriasiform Eruptions During Anti–TNF- Treatment: Psoriasis or Not?—Reply

Gillian C. de Gannes, MD; Mehran Ghoreishi, MD, PhD; Janet Pope, MD, FRCPC; Anthony Russell, MA, MB, BChir, FRCP(C); David Bell, MD, FRCPC; Stewart Adams, MD, FRCPC; Kamran Shojania, MD, FRCPC; Magdalena Martinka, MD, FRCPC; Jan P. Dutz, MD, FRCPC

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In reply

We thank Seneschal et al for their interest in our article. They agree with our observation that most psoriasiform eruptions occurring during anti–TNF- therapy are reported to show histologic findings consistent with psoriasis. However, the authors point out a report of a patient treated with infliximab who developed a symmetrical papular eruption with lichenoid features.¹ They further review 8 cases originally described by their own research group² with histologic findings atypical for psoriasis despite a morphologic description of the lesions as "plaque-type psoriasis" with "pustular lesions of the palms and/or soles." They propose the term lichenoid or spongiotic psoriasiform drug eruption for the reaction. They state that this . . . [Full Text of this Article]

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