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VIGNETTES
Multiple Subcutaneous Lipomas Induced by HAART in the Absence of Protease Inhibitors
Elena Balestreire, BS;
Justin M. Haught, MD;
Joseph C. English III, MD
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We report herein a case of atypical lipodystrophy manifesting as multiple subcutaneous lipomas in a patient with human immunodeficiency virus (HIV) undergoing highly active antiretroviral therapy (HAART) lacking a protease inhibitor.
Report of a Case
A 50-year-old white man presented for evaluation of multiple subcutaneous tumors on his back, chest (Figure 1), neck, abdomen, forearms, and left heel. He was diagnosed 10 months earlier as having HIV infection concurrently with HIV-related non-Hodgkin lymphoma of the diffuse large B-cell type. He stated that the lesions first appeared shortly after the initiation of his HAART, which consisted of the nonnucleoside reverse-transcriptase inhibitor (NNRTI) efavirenz along with tenofovir and lamivudine (2 nucleoside reverse-transcriptase inhibitors [NRTIs]). He received 6 cycles of lymphoma chemotherapy using dose-adjusted infusional etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin. Over the year, his HAART regimen remained the same except that lamivudine . . . [Full Text of this Article]
Comment
AUTHOR INFORMATION
RELATED ARTICLE
Impact of HIV Infection and HAART on Serum Lipids in Men
Sharon A. Riddler, Ellen Smit, Stephen R. Cole, Rui Li, Joan S. Chmiel, Adrian Dobs, Frank Palella, Barbara Visscher, Rhobert Evans, and Lawrence A. Kingsley
JAMA. 2003;289(22):2978-2982.
ABSTRACT
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