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A Glistening Brown Nodule—Diagnosis
Arch Dermatol. 2007;143(2):255-260.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Diagnosis: Pigmented clear cell acanthoma.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
The biopsy specimen demonstrated a well-demarcated area of psoriasiform hyperplasia with elongate rete ridges. There were monomorphic epithelial cells containing abundant pale cytoplasm within the epidermis. A periodic acid–Schiff stain confirmed the presence of glycogen in the cytoplasm. There were a few scattered neutrophils and some hemosiderin. The lesion was diagnosed as a pigmented clear cell acanthoma. Because the lesion was almost completely removed by the biopsy procedure, and because the area had healed well and the nodule had not recurred, no further action was taken.
DISCUSSION
The clear or pale cell acanthoma, also referred to as Degos acanthoma, is usually a red and/or glistening, slightly elevated nodule or dome-shaped plaque, with a "stuck-on" appearance, that typically occurs on the legs of middle-aged or elderly persons.1 It can be crusted or have a collarette of scale,2 and minor trauma can induce bleeding. The lesion in this case was of particular . . . [Full Text of this Article]
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Arch Dermatol. 2007;143(2):255-260.
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