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Brian L. Baker, MD; Carrie A. Fitzgibbons, BS; Lucinda S. Buescher, MD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Calciphylaxis is an uncommon and extremely painful calcifying panniculitis, most often seen in patients with end-stage renal disease. The prognosis is poor, with a 6-month mortality rate ranging from 33% to 80%.¹ Dermatologists are often called on to diagnose the condition, but unfortunately, successful treatments have not been available. We describe a case that responded to treatment with sodium thiosulfate.

Report of a Case

A 68-year-old obese African American woman with a medical history of type 2 diabetes mellitus, hypercholesterolemia, hypertension, coronary artery disease, and congestive heart failure presented with a 1-month history of extremely painful, indurated, depressed plaques with necrotic ulceration and eschar on her outer thighs bilaterally (Figure 1). At that time, her home medications included pioglitazone, aspirin, furosemide, metolazone, amitriptyline, insulin, ranitidine, fosinopril, levothyroxine, atorvastatin, clopidogrel, and carvedilol. Analysis of an incisional biopsy specimen showed areas of . . . [Full Text of this Article]

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RELATED LETTERS

Sodium Thiosulfate as First-Line Treatment for Calciphylaxis
Felix Ackermann, Annabelle Levy, Eric Daugas, Noel Schartz, Anne Riaux, Christian Derancourt, Pablo Urena, and Celeste Lebbé
Arch Dermatol. 2007;143(10):1336-1337.
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Sodium Thiosulfate as First-Line Treatment for Calciphylaxis—Reply
Maria R. Robinson, Joshua J. Augustine, and Neil J. Korman
Arch Dermatol. 2007;143(10):1338.
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Cinacalcet for the Treatment of Calciphylaxis
Maria R. Robinson, Joshua J. Augustine, and Neil J. Korman
Arch Dermatol. 2007;143(2):152-154.
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Sodium Thiosulfate as First-Line Treatment for Calciphylaxis
Ackermann et al.
Arch Dermatol 2007;143:1336-1337.
FULL TEXT  

Sodium Thiosulfate as First-Line Treatment for Calciphylaxis Reply
Robinson et al.
Arch Dermatol 2007;143:1338-1338.
FULL TEXT