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  Vol. 143 No. 3, March 2007 TABLE OF CONTENTS
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Bilateral Symmetrical Nodules on the Feet—Diagnosis

Arch Dermatol. 2007;143(3):417-422.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Athlete's nodules.

GROSS AND MICROSCOPIC FINDINGS

Gross examination of the incisional biopsy specimen revealed a pale white, amorphous, rubbery thickening of the dermis. Histologically, at low magnification, the specimen demonstrated a markedly thickened dermis for this anatomical site, resembling skin from the back (Figure 2). Collagen bundles in the lower reticular dermis also appeared to be thickened. They were splayed apart, with clear space between them (Figure 3). The space between the collagen bundles did not show increased mucin with colloidal iron staining. The stratum corneum and epidermis were unremarkable, and there was no inflammation.


 
Figure appears in full text version.
Figure 2.



 
Figure appears in full text version.
Figure 3.


DISCUSSION

In the early 1990s, Cohen et al1-3 used the term Athlete's nodules to describe benign, acquired, sports-related connective tissue nevi of the collagenous type (collagenomas). These lesions are asymptomatic, firm, flesh-colored, intradermal nodules, often symmetrical, ranging from 0.5 to 4.0 cm in diameter.3 More commonly, the nodules may appear on the knuckles, knees, . . . [Full Text of this Article]


RELATED ARTICLE

Bilateral Symmetrical Nodules on the Feet—Quiz Case
Sharon H. Fang, Michael D. Ioffreda, Jeffrey J. Miller, Klaus F. Helm, and Elizabeth M. Billingsley
Arch Dermatol. 2007;143(3):417-422.
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