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New and Old Therapeutics for Oral Ulcerations
Alison Bruce, MD;
Roy S. Rogers III, MD
Arch Dermatol. 2007;143(4):519-523.
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This month's edition of the Archives of Dermatology has several articles that focus on management and therapeutics for oral mucosal disease. These include a prospective study on the use of pentoxifylline for aphthous ulcers by Thornhill et al1; a retrospective study of medications used in the management of oral lichen planus (OLP) by Torti et al2; and an article by Passeron et al3 discussing a newer agent for control of OLP—pimecrolimus cream.
Oral ulceration is one of the most commonly encountered oral complaints, vexing to both physicians and patients, including those with the troublesome canker sores of recurrent aphthous stomatitis (RAS) as well as those suffering from the persistent ulceration of erosive OLP. These patients are often seen by multiple medical and dental care providers without definitive diagnosis or effective therapy for their oral discomfort. Ulceration of the oral mucosa . . . [Full Text of this Article]
AUTHOR INFORMATION
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A Randomized, Double-blind, Placebo-Controlled Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis
Martin H. Thornhill, Lorena Baccaglini, Elizabeth Theaker, and Michael N. Pemberton
Arch Dermatol. 2007;143(4):463-470.
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Treatment of Oral Erosive Lichen Planus With 1% Pimecrolimus Cream: A Double-blind, Randomized, Prospective Trial With Measurement of Pimecrolimus Levels in the Blood
Thierry Passeron, Jean-Philippe Lacour, Eric Fontas, and Jean-Paul Ortonne
Arch Dermatol. 2007;143(4):472-476.
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Oral Lichen Planus: A Case Series With Emphasis on Therapy
Dorothea C. Torti, Joseph L. Jorizzo, and Martha Ann McCarty
Arch Dermatol. 2007;143(4):511-515.
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