This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Genetics  • Genetic Counseling/ Testing/ Therapy  • Neoplasms  • Nevi  • Alert me on articles by topic

Consequences for Predictive DNA Testing

Wilma Bergman, MD, PhD; Nelleke A. Gruis, PhD

Arch Dermatol. 2007;143(4):525-526.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this issue of the ARCHIVES, Figl and colleagues¹ from Heidelberg, Germany, report a family in which the proband had multiple primary melanomas as well as her mother's sister. During the course of the investigation, the proband's sister was also diagnosed as having melanoma in situ. This familial predisposition is indicative of familial atypical multiple mole melanoma (FAMMM) syndrome, for which the clinical criteria are 2 first-degree relatives with melanoma or 2 cases (even if more distant relatives) if 1 or both have had multiple primary melanomas or 3 or more cases on the same side of the family. The presence of atypical moles is thus irrelevant in respect of the definition of FAMMM, although in most families, individuals with characteristic nevus phenotypes are present.

Out of scientific interest, gene investigations were carried out in the German family. Surprisingly, the . . . [Full Text of this Article]

AUTHOR INFORMATION

RELATED ARTICLES

Store-and-Forward Teledermatology in Skin Cancer Triage: Experience and Evaluation of 2009 Teleconsultations
David Moreno-Ramirez, Lara Ferrandiz, Adoracion Nieto-Garcia, Rafael Carrasco, Pedro Moreno-Alvarez, Rafael Galdeano, Esther Bidegain, Juan J. Rios-Martin, and Francisco M. Camacho
Arch Dermatol. 2007;143(4):479-483.
ABSTRACT | FULL TEXT  

Melanoma Outcomes for Medicare Patients: Association of Stage and Survival With Detection by a Dermatologist vs a Nondermatologist
Michelle L. Pennie, Seaver L. Soon, Jessica B. Risser, Emir Veledar, Steven D. Culler, and Suephy C. Chen
Arch Dermatol. 2007;143(4):488-494.
ABSTRACT | FULL TEXT  

Multiple Melanomas After Treatment for Hodgkin Lymphoma in a Non-Dutch p16-Leiden Mutation Carrier With 2 MC1R High-Risk Variants
Adina Figl, Ranjit K. Thirumaran, Selma Ugurel, Andreas Gast, Kari Hemminki, Rajiv Kumar, and Dirk Schadendorf
Arch Dermatol. 2007;143(4):495-499.
ABSTRACT | FULL TEXT  

Melanoma of the Foot and Ankle: A Case Series of an Underrecognized Entity
Hubert T. Greenway, Jr, Joy M. Twersky, Shanna B. Meads, and Benjamin F. Kelley
Arch Dermatol. 2007;143(4):543-544.
EXTRACT | FULL TEXT