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VIGNETTES
Peristomal Pyoderma Gangrenosum Associated With Collagenous Colitis
Mark D. P. Davis, MD;
Krystal J. Holderness Nakamura, MD
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We recently observed a patient with peristomal pyoderma gangrenosum, superficial granulomatous type, associated with collagenous colitis.
Report of a Case
A 52-year-old woman presented with painful peristomal ulcers. The ulcers (Figure 1) began 2 weeks after she had a diverting Brooke ileostomy and total colectomy to treat intractable diarrhea caused by a combination of collagenous colitis and pelvic floor dysfunction. The diarrhea had been recalcitrant to treatment and had led to considerable and disabling difficulties with frequent liquid bowel movements and incontinence necessitating her stopping work. She had no history of ulcers.
Figure appears in full text version.
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Figure 1. Ulcers surrounding stoma consistent with pyoderma gangrenosum.
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Biopsy specimens of the ulcers showed cutaneous ulceration and dermal suppurative granulomatous inflammation. Test results for microorganisms (Gomori methenamine silver, gram, and Fite stains) were negative. Cultures for mycobacteria, fungi, bacteria, and viruses all showed negative results except for Staphylococcus aureus. . . [Full Text of this Article] Comment
AUTHOR INFORMATION
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