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Arch Dermatol. 2007;143(6):791-796.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Microcystic adnexal carcinoma (MAC).

MICROSCOPIC FINDINGS

Medium-power microscopy demonstrated a poorly circumscribed tumor consisting of large keratin-filled cysts in the middle and upper dermis and collections of basaloid cells throughout the entire dermis. Some of the tumor cells were organized into ductal structures, while others infiltrated the deepest portions of the dermis as single cells. Dense, hyalinized, desmoplastic stroma separated nests of tumor cells. Tumor extended to the lateral and deep margins of the biopsy specimen. Higher magnification revealed perineural infiltration (Figure 3). Only minimal cytologic atypia was present, and no mitotic figures were identified.

Figure appears in full text version. Figure 3.

DISCUSSION

Microcystic adnexal carcinoma is a rare, slow-growing, locally invasive tumor. It occurs most commonly on the head and neck, with a predilection for the central area of the face.^1-3 Excessive UV exposure¹ and radiation therapy² may be predisposing factors. While MAC may appear at any age, most cases are diagnosed in the sixth and seventh decades of . . . [Full Text of this Article]

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Arch Dermatol. 2007;143(6):791-796.
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