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Arch Dermatol. 2007;143(6):791-796.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Eosinophilic cellulitis (Wells syndrome).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histologic examination of the biopsy specimen revealed superficial and deep mixed inflammatory infiltrates composed of lymphocytes, histiocytes, and numerous eosinophils. The epidermis showed areas of spongiosis and a few dyskeratotic keratinocytes, while there was prominent edema of the papillary dermis (Figure 2). There were also collagen bundles surrounded by dense infiltrates of lymphocytes, histiocytes, and numerous eosinophils with their surrounding degranulated contents, creating histologic flame figures (Figure 3). Oral prednisone and cetirizine therapy was initiated, and a 1-week follow-up visit revealed partial resolution of the lesions.

Figure appears in full text version. Figure 2.

Figure appears in full text version. Figure 3.

DISCUSSION

Eosinophilic cellulitis, or Wells syndrome, is a rare but distinct dermatosis that was first described in 1971 as "recurrent granulomatous dermatitis with eosinophilia."¹ The lesions have a clinical appearance that resembles acute cellulitis or bullous erysipelas and characteristic histopathologic features of dermal edema and a dense eosinophilic infiltrate, creating what has been described as flame figures. . . [Full Text of this Article]

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Arch Dermatol. 2007;143(6):791-796.
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