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Sanghamitra Chakrabarti, MRCP; Diane Williamson, MRCP
Glan Clwyd Hospital, Denbighshire, Wales

Arch Dermatol. 2007;143(6):791-796.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 70-year-old woman presented with a 3-week history of pain and redness of her right calf followed by the development of an exquisitely painful, rapidly enlarging ulcer. There was no history of trauma or associated systemic upset. Her medical history was notable for adult polycystic kidney disease requiring hemodialysis after chronic rejection of a cadaveric kidney transplant. A malignant melanoma (Breslow thickness 5.2 mm) had also been excised from the patient's left thigh in June 2003. Her medications included warfarin sodium for previous deep vein thrombosis and pulmonary embolism, prednisolone (10 mg/d), simvastatin (20 mg/d), temazepam (10 mg/d), omeprazole (40 mg/d), and aluminum hydroxide (475 mg 3 times a day).

Physical examination revealed a 5.0 x 2.5-cm area of ulceration covered with black eschar on the right calf (Figure 1). There were a few nonpalpable purpuric lesions on the surrounding skin. Peripheral . . . [Full Text of this Article]

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A Rapidly Enlarging Necrotic Ulcer on the Right Calf—Diagnosis
Arch Dermatol. 2007;143(6):791-796.
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