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COMMENTS AND OPINIONS
Fast-Growing and Slow-Growing Melanomas
Giuseppe Argenziano, MD;
Iris Zalaudek, MD;
Gerardo Ferrara, MD
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We read with great interest the article by Liu et al1 and the accompanying editorial by Lipsker2 on rapidly growing melanomas. Both articles point out that different types of melanomas exist in relation to their biological propensity to grow and metastasize. Based on patient recall, Liu et al1 calculated the rate of growth of 404 invasive melanomas (median tumor thickness, 1.3 mm) and found that almost a third of them grew 0.5 mm per month or more. These rapidly growing melanomas are more likely thick tumors associated with a high mitotic rate and more frequently found in older men with fewer melanocytic nevi and freckles. Furthermore, they usually lack the clinical ABCD features of melanoma (A, asymmetry; B, border irregularity; C, color variegation; D, diameter >5 mm), being frequently symmetric and amelanotic nodules. The authors conclude that the lack of the . . . [Full Text of this Article]
AUTHOR INFORMATION
RELATED LETTERS
Fast-Growing and Slow-Growing Melanomas—Reply
John W. Kelly, Grant A. McArthur, Rory Wolfe, John F. Thompson, and Wendy Liu
Arch Dermatol. 2007;143(6):803-804.
EXTRACT
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Increasing Ratio of Thin to Thick Melanoma Lesions: Pathogenesis and Early Detection of This Cancer—Reply
Dan Lipsker
Arch Dermatol. 2007;143(6):804-805.
EXTRACT
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RELATED ARTICLES
Rate of Growth in Melanomas: Characteristics and Associations of Rapidly Growing Melanomas
Wendy Liu, John P. Dowling, William K. Murray, Grant A. McArthur, John F. Thompson, Rory Wolfe, and John W. Kelly
Arch Dermatol. 2006;142(12):1551-1558.
ABSTRACT
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Growth Rate, Early Detection, and Prevention of Melanoma: Melanoma Epidemiology Revisited and Future Challenges
Dan Lipsker
Arch Dermatol. 2006;142(12):1638-1640.
EXTRACT
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