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VIGNETTES
Hypereosinophilic Syndrome With Peripheral Circulatory Insufficiency and Cutaneous Microthrombi
Takahiro Hamada, MD;
Yoko Kimura, MD;
Shinsuke Hayashi, MD;
Takekuni Nakama, MD;
Takashi Hashimoto, MD
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Report of a Case
A 23-year-old Japanese man was referred to our hospital, complaining of a 1-month history of livedo reticularis, painful erythematous indurated patches, and Raynaud phenomenon on the hands and feet (Figure 1A). Although he was a cigarette smoker, he had no atopic diathesis or related disorders and no history of diabetes mellitus, hepatitis C, or drug exposure.
Figure appears in full text version.
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Figure 1. Clinical features of the patient. A, Erythematous indurated patches and Raynaud phenomenon on the right hand. B, Features were improved with mild purpura on the fingertips after administration of prednisolone.
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Laboratory investigations revealed a persistent eosinophilia (7191 white blood cells/µL; normal, <500 cells/µL) and elevated levels of eosinophilic cationic protein (101 µg/mL; normal, <14.7 µg/mL). Serum IgE level was 1103 µg/L (normal, <726 µg/L). The results of renal function tests, including urinalysis, creatinine and serum . . . [Full Text of this Article]
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AUTHOR INFORMATION
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