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Arch Dermatol. 2007;143(7):937-942.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Prostate cancer metastatic to the skin.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Microscopic examination demonstrated numerous glandular structures composed of atypical cells in the dermis (Figures 2 and 3). Immunohistochemical stains were positive for prostate-specific antigen and negative for cytokeratin AE1/AE3. Thus, the histologic findings were consistent with cutaneous metastasis of prostate cancer. Further investigations revealed extensive metastases to the brain, bladder, bones, and skin. The patient underwent palliative bilateral orchiectomy and radiation therapy to the cervical spine, thoracic spine, and right clavicle. He died 17 days after admission following an acute change in mental status.

Figure appears in full text version. Figure 2.

Figure appears in full text version. Figure 3.

DISCUSSION

Prostate cancer is the most common malignancy and the second most common cause of death in men.¹ It is typically an adenocarcinoma with a high rate of metastasis to the bones, liver, lungs, and adrenal glands.² The overall incidence of cutaneous metastasis from all visceral malignancies is uncommon, at 5.3%.³ Of the visceral malignancies with cutaneous manifestations, prostate cancer has . . . [Full Text of this Article]

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Arch Dermatol. 2007;143(7):937-942.
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