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COMMENTS AND OPINIONS
Paraneoplastic Relapsing Polychondritis
Philip R. Cohen, MD
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I read with interest the report by Yanagi et al1 in which the authors not only describe a 60-year-old Japanese woman with newly diagnosed relapsing polychondritis 3 years following the detection and subsequent successful treatment of stage IIA splenic non-Hodgkin lymphoma but also speculate that some cases of relapsing polychondritis may be paraneoplastic. Mucocutaneous paraneoplastic syndromes may be associated with hematologic malignant neoplasms, solid tumors, or both.2 Also, albeit less commonly, individuals with cancer may concurrently or sequentially demonstrate more than 1 mucocutaneous paraneoplastic syndrome.3-4
The potential association of relapsing polychondritis in patients who have or subsequently develop myelodysplastic syndrome is well established.5 In addition to lymphoma, paraneoplastic relapsing polychondritis has also occurred in patients with other hematologic malignant neoplasms and dyscrasias, including aplastic anemia, dysgammaglobulinemia, various leukemias, myeloma, and myeloproliferative disorders.5 Individual reports have also been published of paraneoplastic relapsing polychondritis in oncology patients with . . . [Full Text of this Article] AUTHOR INFORMATION
RELATED ARTICLE
Relapsing Polychondritis and Malignant Lymphoma: Is Polychondritis Paraneoplastic?
Teruki Yanagi, Tetsuri Matsumura, Ryuta Kamekura, Noriko Sasaki, and Satoshi Hashino
Arch Dermatol. 2007;143(1):89-90.
ABSTRACT
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