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VIGNETTES
Success of Goeckerman Treatment in 2 Patients With Psoriasis Not Responding to Biological Drugs
Temitope F. Soares, PharmD, MD;
Mark D. P. Davis, MD
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Goeckerman treatment was effective for 2 patients referred to Mayo Clinic with psoriasis not responding to treatment with biological agents. In patient 1, psoriasis flaring during etanercept therapy cleared completely with Goeckerman treatment; in patient 2, psoriasis not responding to etanercept and alefacept therapy cleared with Goeckerman treatment and with the initiation of highly active antiretroviral therapy (HAART) for newly diagnosed human immunodeficiency virus (HIV).
Report of Cases
Case 1
Patient 1 was a 22-year-old man who had a 5-year history of psoriasis that was recalcitrant to treatment with topical corticosteroids, methotrexate, and psoralen UV-A (PUVA). He received etanercept therapy for 18 months before presentation and reported mixed results, but his lesions never completely cleared. While taking etanercept, he had an acute flare of symptoms, with multiple guttate psoriatic plaques covering about 70% of his skin. A throat swab tested positive for Streptococcus pyogenes; . . . [Full Text of this Article] Case 2 Comment
AUTHOR INFORMATION
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Arch Dermatol 2007;143:912-915.
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