 |
|
Erythematous Papules and Plaques Involving the Groin and Scrotum—Diagnosis
Arch Dermatol. 2007;143(8):1067-1072.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Diagnosis: Cutaneous metastases of transitional cell carcinoma.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Histologic examination of the biopsy specimen revealed proliferating nests and cords of balloon-shaped cells infiltrating into the dermis, with a narrow, uninvolved grenz zone beneath the epidermis. The individual cells contained hyperchromatic, atypical nuclei with frequent mitosis and abundant cytoplasm. These histologic findings were consistent with primary transitional cell urothelial carcinoma. Magnetic resonance imaging also revealed diffuse metastatic disease to the brain. Our patient received hospice care and palliative radiation therapy for his metastatic disease. A topical corticosteroid cream (0.025% triamcinolone) was prescribed for symptomatic relief of the intermittent pruritus and pain that were associated with the skin lesions.
DISCUSSION
Bladder cancer is the most common cancer affecting the urinary system.1 In the United States, approximately 80% of cases are diagnosed in patients older than 60 years, with males being affected more than females. It occurs more commonly in industrialized nations and is associated with several environmental exposures, including arylamines, cigarette . . . [Full Text of this Article]
RELATED ARTICLE
Erythematous Papules and Plaques Involving the Groin and Scrotum—Quiz Case
Jennifer Breedlove, Sunghun Cho, and Sean Gunning
Arch Dermatol. 2007;143(8):1067-1072.
EXTRACT
| FULL TEXT
|
