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Hyperpigmented Keratotic Nodules—Quiz Case
Ser Ling Chua, MRCP;
Kusum Kulkarni, MRCPath;
Eric Saihan, FRCP
Queen's Medical Centre, Nottingham, England
Arch Dermatol. 2007;143(9):1201-1206.
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REPORT OF A CASE
A 59-year-old woman of Indian descent presented with a 6-month history of an increasing number of itchy hyperpigmented nodules on her trunk and limbs. The lesions were preceded by pruritus. Treatment with topical 0.05% clobetasone butyrate cream and oral cetirizine reduced the pruritus but did not affect the appearance of the lesions. The patient had a history of type 2 diabetes mellitus and hypertension. Ultrasonography showed that her liver was enlarged, with a fatty echo texture.
Physical examination revealed multiple 3- to 15-mm-diameter hyperpigmented lesions with a central keratotic plug (Figure 1). The Koebner phenomenon was seen (Figure 2). There was sparing of her back in "difficult-to-reach" areas. A 4-mm punch biopsy specimen obtained from a lesion on the left upper back area was sent for histopathologic examination (Figure 3).
Figure appears in full text version.
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Figure appears in full text version.
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Hyperpigmented Keratotic Nodules—Diagnosis
Arch Dermatol. 2007;143(9):1201-1206.
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