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  Vol. 143 No. 9, September 2007 TABLE OF CONTENTS
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Tender Nodules on the Palms and Soles—Diagnosis

Arch Dermatol. 2007;143(9):1201-1206.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Palmoplantar eccrine hidradenitis (PEH).

MICROSCOPIC FINDINGS

Examination of the hematoxylin-eosin–stained skin biopsy specimen from the erythematous tender nodule revealed a dense neutrophilic inflammatory infiltrate around the eccrine sweat glands.

DISCUSSION

Palmoplantar eccrine hidradenitis is a distinct entity with characteristic clinical findings. First reported in 1988, it was named traumatic plantar urticaria.1 Since then, 47 cases have been reported under 5 different names, including idiopathic (palmo)plantar hidradenitis and recurrent palmoplantar hidradenitis.2 It primarily affects healthy children and is characterized by an abrupt appearance of erythematous, tender nodules on the palms and soles that may last 1 to 4 weeks and cause considerable difficulty in walking.2 Most eruptions are limited to the plantar surfaces, although palmar lesions have been documented.3 Typical histiologic findings include a neutrophilic perieccrine infiltrate in the setting of varying degrees of superficial and deep perivascular infiltrates of neutrophils, lymphocytes, and histiocytes as well as septal panniculitis.3

The etiology of PEH remains unknown. Local mechanical . . . [Full Text of this Article]







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