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COMMENTS AND OPINIONS
Evidence Insufficient to Recommend Melanoma Surveillance Following Phototherapy for Jaundice
Thomas B. Newman, MD, MPH;
M. Jeffrey Maisels, MB BCh
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Matichard et al1 reported an association between receipt of blue-light phototherapy for neonatal jaundice and numbers of melanocytic nevi at least 2 mm in diameter at age 8 or 9 years. Although they stated that their results "should be interpreted with caution,"1(p1603) they concluded that exposed children "should undergo dermatologic preventive measures and surveillance for the development of melanoma."1(p1599)
We believe that this recommendation is premature. The authors studied only 18 children who had been exposed to phototherapy, and the selection of these exposed children was via an entirely different mechanism from the selection of the control group. This could easily have introduced confounding factors that were not measured. It appears that the original hypothesis that the authors sought to test was that phototherapy might increase the total nevus count, which it did not: mean counts, 28.5 vs 28.7 (. . . [Full Text of this Article]
AUTHOR INFORMATION
RELATED LETTER
Evidence Insufficient to Recommend Melanoma Surveillance Following Phototherapy for Jaundice—Reply
Vincent Descamps
Arch Dermatol. 2007;143(9):1216-1217.
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RELATED ARTICLE
Effect of Neonatal Phototherapy on Melanocytic Nevus Count in Children
Emmanuelle Matichard, Anne Le Hénanff, Alfred Sanders, Jocelyne Leguyadec, Beatrice Crickx, and Vincent Descamps
Arch Dermatol. 2006;142(12):1599-1604.
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