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Lucio Bakos, MD, PhD; Renato Marchiori Bakos, MD, MSc

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Tacrolimus is a macrolide antibiotic produced by Streptomyces tsukubaensis and with strong T-specific immunosuppressant activity. Primarily used for treatment of atopic dermatitis, it has been used to treat other inflammatory and immunologic skin disorders, including vitiligo, with encouraging results.¹ Focal hypertrichosis has been reported during topical tacrolimus therapy for childhood vitiligo,² but acne does not seem to be a frequently reported adverse effect.

Report of a Case

An 18-year-old woman presented with vitiligo on the left side of her chin and neck and on both sides of the dorsum. The lesions had been present for 4 months and had been enlarging progressively. Findings of clinical evaluation and laboratory tests were all normal. As a first treatment, she had undergone a 3-month course of topical 0.05% desonide cream without any clinical response. She was put on a regimen of topical 0.1% tacrolimus, applied at bedtime, for . . . [Full Text of this Article]

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