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Successful Treatment of Toenail Onychomycosis With Photodynamic Therapy
Daisuke Watanabe, MD, PhD;
Chiharu Kawamura, MD;
Yuko Masuda, MD;
Yoichi Akita, MD, PhD;
Yasuhiko Tamada, MD, PhD;
Yoshinari Matsumoto, MD, PhD
Arch Dermatol. 2008;144(1):19-21.
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INTRODUCTION
Although recent progresses in oral antifungal agents have made it possible to treat onychomycosis effectively, these drugs can have considerable adverse liver or kidney effects and medication interactions in special populations such as children, the elderly, and patients with underlying systemic diseases. We describe 2 patients with toenail onychomycosis who were sucessfully treated with photodynamic therapy (PDT).
REPORT OF CASES
CASE 1
An 80-year-old Japanese woman presented with a 3-year history of asymptomatic alterations of the toenails of her right foot. She also had Sjögren syndrome, which was well controlled. She had been diagnosed as having onychomycosis and had been treated with topical terbinafine for 2 years, without success. She did not take any oral antifungal agents because of her advanced age. Physical examination revealed white patches on the surface and distal undersurface . . . [Full Text of this Article] CASE 2
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
Aichi Medical University, Nagakute, Japan
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