Diagnosis: Pachydermodactyly.
MICROSCOPIC AND LABORATORY FINDINGS
Histopathologic analysis of the skin biopsy specimen showed increased dermal collagen (Figure 2) and increased mucin deposits (Figure 3).
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DISCUSSION
Pachydermodactyly is a rare disorder first described by Bazex and Teillard1 in 1973. To date, only about 60 cases of this benign condition have been reported worldwide. Female patients with the disorder have been described, although rarely2; it primarily occurs in young males, generally in adolescence or young adulthood.3
Clinically, there is bilateral asymptomatic swelling of the soft tissues surrounding the PIP joints, most frequently of the second through fourth digits, but sometimes also involving both of the fifth digits. There is no underlying joint swelling or other joint abnormalities. Radiographs show only the soft-tissue swelling without underlying bony erosion or articular damage, and all laboratory test results are generally unremarkable. Histopathologic examination of involved skin tissue demonstrates an increase in dermal . . . [Full Text of this Article]
