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Multiple Nodules in a Child—Diagnosis
Arch Dermatol. 2008;144(2):255-260.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Diagnosis: Proliferative fasciitis.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Results of histologic examination of the nodule revealed a lesion with an indistinct margin extending from the deep dermis to the fatty tissue. The nodule comprised spindle-shaped fibroblastlike cells intermingled with gangliocytelike giant cells with abundant eosinophilic cytoplasm and large nuclei with prominent nucleoli. The interstitium was primarily composed of a mucinous matrix with few collagen fibers. Typical mitoses were observed. Within 4 weeks, a spontaneous regression of all nodules was observed without any treatment; within 3 months, all the nodules completely disappeared.
DISCUSSION
Proliferative fasciitis is a rapidly growing, benign, reactive process of unknown etiology. Chung and Enzinger1 separated proliferative fasciitis from nodular fasciitis based on the presence of basophilic, mitotically active, ganglionlike giant cells in the latter. It usually occurs inmiddle-aged adults of both sexes, particularly on the limbs,2 but pediatric cases have been recently described.3-5 Typically, lesions appear as rapidly growing, painful nodules occurring after trauma.6 The list . . . [Full Text of this Article]
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Multiple Nodules in a Child—Quiz Case
Giuseppe Fabrizi, Calogero Pagliarello, and Guido Massi
Arch Dermatol. 2008;144(2):255-260.
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