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Violaceous Purpuric Plaques on the Lower Extremity—Diagnosis
Arch Dermatol. 2008;144(3):405-410.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Diagnosis: Pigmented purpuric lichenoid dermatitis (Gougerot-Blum syndrome).
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Microscopic evaluation revealed a bandlike lymphohistiocytic infiltrate with multiple foci of prominent extravasation of red blood cells in the papillary dermis. The epidermis was slightly hyperplastic, lacked significant spongiosis, and was surmounted by hyperkeratotic scale with focal parakeratosis. The lymphocytes lacked cytologic atypia. On the basis of these findings, the lichenoid variant of pigmented purpuric dermatitis (PPD) was favored over the eczematoid variant of Doucas and Kapetanakis. Treatment with clobetasol propionate ointment, twice daily for 2 weeks on, alternating with 2 weeks off, was initiated for a 2- to 3-month trial. This regimen resulted in decreased erythema and flattening of the plaques, which recurred after the clobetasol therapy was discontinued.
DISCUSSION
Pigmented purpuric lichenoid dermatitis, also known as Gougerot and Blum syndrome, is 1 of the 5 traditional variants of PPD. The others are progressive PPD (Schamberg disease), purpura annularis telangiectoides (Majocchi disease), lichen aureus, and eczematoidlike purpura of Doucas and . . . [Full Text of this Article]
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