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VIGNETTES
Linear and Whorled Nevoid Hypermelanosis: Unique Clinical Presentations and Their Possible Association With Chromosomal Abnormality inv(9)
Seung Phil Hong, MD;
Seok-Yong Ahn, MD;
Won-Soo Lee, MD
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Linear and whorled nevoid hypermelanosis (LWNH) is characterized by swirls and streaks of macular hyperpigmentation along the Blaschko line and usually appears within the first 2 years of life without preceding inflammation or atrophy.1 It is occasionally associated with chromosomal abnormalities and anomalies of other organs.2
Report of a Case
A 33-year-old Korean man presented with multiple hyperpigmented streaks covering his whole body. The lesions first appeared in infancy and were localized to a small area of the body with linear pigmented patches. Starting in adolescence, the skin lesions spread over the entire body without definite inflammation and vesicular eruption.
Physical examination revealed dark brown reticulate macules arranged in streaks along the Blaschko line (Figure 1). The patient also had bilateral partial syndactyly between his third and fourth toes. Dental and ophthalmologic evaluations revealed no abnormalities. There was no significant family or . . . [Full Text of this Article]
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