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Arch Dermatol. 2008;144(4):547-552.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Multifocal proliferating epidermoid cysts.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Microscopic examination revealed irregular epidermal hyperplasia with a central cystic invagination communicating with the surface. Arising from this cystic lesion were numerous, irregular, well-differentiated lobules of squamous epithelium with infundibular-type keratinization. No notable atypia was identified. The diagnosis of multifocal proliferating epidermoid cysts was made. The patient was treated by excision of the lesions.

DISCUSSION

Proliferating epidermoid cyst (PEC) is a rare neoplasm arising from the epithelium of the hair follicle. The term was first coined by Jones¹ in 1966 to describe what we now call "proliferating trichilemmal cyst" (PTC). It was not until 1995 that the 2 types of epithelial tumors were distinguished on clinical and histopathological grounds by Sau et al,² and their report to our knowledge remains the only reported series on PEC to date.

In contrast to PTC, most cases of PEC (79%) involve areas outside of the scalp, including the anogenital areas, upper extremities, and trunk. . . . [Full Text of this Article]

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Arch Dermatol. 2008;144(4):547-552.
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