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  Vol. 144 No. 4, April 2008 TABLE OF CONTENTS
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Bluish Subcutaneous Nodule in a Child—Diagnosis

Arch Dermatol. 2008;144(4):547-552.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Fibrous hamartoma of infancy.

MICROSCOPIC FINDINGS

The biopsy findings showed a subcutaneous proliferation with 3 different tissue components: trabeculae of interlacing fibrous tissue, nests or whorls of spindle cells in a mucinous matrix (mesenchymal cells), and mature fat. Fibrous trabeculae, composed of spindle-shaped cells in a densely collagenous stroma, intersected mature fat lobules and nests of immature spindle-shaped to stellate cells in myxoid stroma.

DISCUSSION

Fibrous hamartoma of infancy (FHI) is a rare, benign, mesenchymal tumor that can occur congenitally or appear during early childhood, with 90% of cases arising within the first year of life.1 The tumor is usually slow growing, although it may initially undergo a period of rapid growth.2 Generally, FHI presents as a painless, freely movable, firm, solitary mass, but cases of multiple synchronous lesions have been reported.3 A solitary lesion may also consist of multiple nodules. Typically, FHI lesions range from 0.5 to 4.0 cm in diameter, but lesions as large as . . . [Full Text of this Article]


RELATED ARTICLE

Bluish Subcutaneous Nodule in a Child—Quiz Case
Kristy F. Davis, Jashin J. Wu, Senait W. Dyson, and Brandie J. Metz
Arch Dermatol. 2008;144(4):547-552.
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