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Katharina C. Kaehler, MD; Paul A. J. Russo, MD; Friederike Egberts, MD; Patrick H. Warnke, MD, DMD; Lorenzo Cerroni, MD; Axel Hauschild, MD

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Primary oral melanoma is a rare tumor that has been estimated to represent 0.1% of melanoma cases in whites.¹ A review of 20 cases of tongue melanomas¹ and a literature survey in PubMed revealed a total of 32 published cases. One-third of patients diagnosed as having primary oral melanoma also had preexisting pigmented lesions at the same site. The prognosis is poor, with a 5-year survival rate of only 26.4%.² We report a lethal case of primary melanoma of the tongue that developed within an oral melanosis that had been biopsied 9 years before its malignant transformation.

Report of a Case

A 57-year-old man without a family history of melanoma presented in February 1993 with histologically confirmed leukokeratosis of the lower lip. Physical examination also revealed a bluish brown melanosis of . . . [Full Text of this Article]

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