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Giant Subcutaneous Tumors on the Thighs—Diagnosis
Arch Dermatol. 2008;144(6):795-800.
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Diagnosis: Dendritic fibromyxolipoma.
MICROSCOPIC FINDINGS AND CLINICAL COURSE
Histopathologic analysis demonstrated mature adipocytes, keloidal collagen, and multiple fibroblasts with slender dendritic processes within a myxoid stroma. No lipoblasts were seen. The dendritic cells stained positive for CD34; the adipocytes stained positive for S-100; and the Ki-67 stain showed a low growth fraction. The larger tumor was then completely removed by simple excision. The excised tumor weighed more than 145 kg. The second tumor was scheduled to be excised at a later date, after the first incision site was healed.
DISCUSSION
Dendritic fibromyxolipoma is a rare, benign, soft tissue lesion first described by Suster et al.1 To our knowledge, only 13 cases of this lesion have been reported, most appearing in adult men aged 33 to 81 years.1-2 Most tumors are located on the head, neck, chest, and back. These are large tumors, 2 to 11 cm in diameter (mean diameter, 6 cm), but the greatest dimension of this patient's . . . [Full Text of this Article]
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Giant Subcutaneous Tumors on the Thighs—Quiz Case
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Arch Dermatol. 2008;144(6):795-800.
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