This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Bullous Diseases  • Hypersensitivity  • Diagnosis  • Allergy  • Alert me on articles by topic

Arch Dermatol. 2008;144(6):795-800.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Skin pathergy reaction in Behçet disease.

MICROSCOPIC FINDINGS, LABORATORY FINDINGS, AND CLINICAL COURSE

Histopathologic examination revealed a widespread necrosis of the epidermis with blister formation and a massive neutrophilic infiltrate in the upper part of the dermis. Fibrin deposits in the vessel walls with intraluminal thrombi were present, as well as focal nuclear dust and hemorrhages (Figure 3). Findings from complete blood cell count and blood chemistry analysis and levels of antinuclear antibodies and antiphospholipid antibodies were within reference range. The patient expressed the HLA-B51 antigen. Findings from ocular examination as well as neurologic workup were within reference range. Our patient received a topical steroid to treat the lesions on the arms and dapsone systemically. The lesions on her arms resolved within a few days, whereas the oral and genital ulcers healed within a few months. At her 18-month follow-up visit, the patient was free of cutaneous and mucosal lesions while receiving dapsone, 50 mg, every other day.

Figure appears in full text version. Figure 3.

DISCUSSION

The . . . [Full Text of this Article]

RELATED ARTICLE

Bullous Lesions Arising After a Skin Prick Test—Quiz Case
Cesare Massone, Elisabeth Aberer, Alexandra Maria Giovanna Brunasso, and Lorenzo Cerroni
Arch Dermatol. 2008;144(6):795-800.
EXTRACT | FULL TEXT