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Nodular Eruption on the Feet, Knees, and Dorsal Surface of the Hands of a 34-Year-Old HIV-Positive Man—Quiz Case
Jeffrey S. Newman, MD, PhD;
Maxwell A. Fung, MD
University of California at Davis Medical Center, Sacramento
Arch Dermatol. 2008;144(7):933-938.
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REPORT OF A CASE
A 34-year-old human immunodeficiency virus (HIV)– and hepatitis C–positive man developed disfiguring nodules on his feet, hands, and knees over a 3-month period. The individual lesions were asymptomatic; however, the bulkiness of the lesions on his feet impeded ambulation. His CD4 lymphocyte count was 170/µL (reference range, 490/µL-1740/µL), and his HIV viral load was more than 105 copies/µL. Serologic tests were negative for serum cryptococcal antigen and rapid plasmin reagin. His medications were tenofovir plus emtricitabine, atazanavir, trimethoprim-sulfamethoxazole, fluconazole, paroxetine hydrochloride, venlafaxine, methadone, and fentanyl.
Physical examination revealed firm, pink nodules involving both the plantar and dorsal surfaces of the feet and toes (Figure 1 and Figure 2). Similar-appearing nodules were evident over the knees, and there were small pink nodules on the dorsum of the left hand. A large nodular lesion from the left knee (not depicted but . . . [Full Text of this Article]
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