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COMMENTS AND OPINIONS
Eczematoid Graft-vs-Host Disease
Robert H. Cook-Norris, MD;
Roger H. Weenig, MD
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We read with interest the report by Creamer et al1 in the September issue of the Archives, which described 10 patients with eczematoid dermatitis that occurred after allogeneic hematopoietic stem cell transplantation. The authors considered this eruption to represent a novel form of chronic cutaneous graft-vs-host disease (GVHD). We have seen several bone marrow transplant recipients who presented with a similar eruption and considered them to have one of the papulosquamous variants of GVHD and not a novel form. The decision to restrict or separate various presentations of a disease may be regarded as "lumping" or "splitting" and is the rationale for classification schemes. Creamer and colleagues suggest that a distinction of this clinical presentation of GVHD is important because all 10 patients developed erythroderma and had substantial associated morbidity and mortality. However, the increased morbidity and mortality might be attributable . . . [Full Text of this Article]
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RELATED ARTICLE
Eczematoid Graft-vs-Host Disease: A Novel Form of Chronic Cutaneous Graft-vs-Host Disease and Its Response to Psoralen–UV-A Therapy
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ABSTRACT
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RELATED LETTER
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Arch Dermatol. 2008;144(8):1066-1067.
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