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  Vol. 144 No. 9, September 2008 TABLE OF CONTENTS
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The Nikolskiy Sign

Jennifer Channual, BS; Jashin J. Wu, MD

Arch Dermatol. 2008;144(9):1140.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In 1894, Russian dermatologist Pyotr Vasiliyevich Nikolskiy, MD (Figure), reported a mechanical phenomenon that would later be internationally recognized by the eponym crediting his name–the Nikolsky sign.1 (His name was originally spelled Nikolskiy, but it is more commonly referenced as Nikolsky.1) In 1896, his thesis on pemphigus foliaceus described the clinical finding, and his later work suggested that the underlying pathologic process was acantholysis occurring in affected areas as well as in areas with intact, normal-appearing skin.


Figure 1
Figure. Pyotr Vasiliyevich Nikolskiy, MD (1858-1940), was a professor and head of the Department of Dermatology at Warsaw University (1898-1915) in Poland and subsequently served as head of the Department of Dermatology and Venereology at North-Caucasian University in Rostov-on-Don, Russia.


A review of the literature on the Nikolsky sign interestingly reveals a history of disagreement about its exact definition and method . . . [Full Text of this Article]



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